Inhibitori piridilici di trasduzione del segnale hedgehog

Inhibitori piridilici di trasduzione del segnale hedgehog

The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I:wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.

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Bibliographische Detailangaben
Hauptverfasser: GUNZER JANET L, MALESKY KIMBERLY, WANG SHUMAI, REYNOLDS MARK E, SUTHERLIN DANIEL P, STANLEY MARK S, LALONDE REBECCA L, BAO LIANG, SAVAGE SCOTT J, DINA MICHAEL S, CASTANEDO GEORGETTE
Format: Patent
Sprache:ita
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Beschreibung
Zusammenfassung:The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I:wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.