Chinazoline per l'inibizione di pdk1

The invention provides novel compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.

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Bibliographische Detailangaben
Hauptverfasser: MURRAY JEREMY M, BASHAM STEVEN E, DOVE JEFFREY H, WARNE ROBERT L, SHU WEI, RICO ALICE, WANG XIAOJING M, LIN XIAODONG, AMIRI PAYMAN, ZHOU YASHEEN, AIKAWA MINA E, JAIN RAMA, RAMURTHY SAVITHRI, SUBRAMANIAN SHARADHA
Format: Patent
Sprache:ita
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Beschreibung
Zusammenfassung:The invention provides novel compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.