NITRATEALKANE CARBOXYLIC ACID DERIVATIVES, METHOD OF THEIR PREPARATION, THEIR USING AND MEDICINE CONTENTS THESE MATTERS

NITRATEALKANE CARBOXYLIC ACID DERIVATIVES, METHOD OF THEIR PREPARATION, THEIR USING AND MEDICINE CONTENTS THESE MATTERS

Nitratoalkanoic acid derivatives of the general formula (I), in particular containing N-acylamino acids or N-acylpeptides, of the general formula (I) in which the symbols have the meanings mentioned in the claims. They are distinguished by advantageous physicochemical properties and good physiologic...

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Bibliographische Detailangaben
Hauptverfasser: KANZLER RALF, FRITSCHI EDGAR, NOACK EIKE, FEELISH MARTIN, SANDROCK KLAUS
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Nitratoalkanoic acid derivatives of the general formula (I), in particular containing N-acylamino acids or N-acylpeptides, of the general formula (I) in which the symbols have the meanings mentioned in the claims. They are distinguished by advantageous physicochemical properties and good physiological tolerability for active substances already preventing known nitrate tolerance or weakening a tolerance which has already set in. The compounds are used in medicaments for the treatment of circulatory disorders, high blood pressure, cardiac insufficiency and for dilating the peripheral vessels.