LIPOSOMIC NIFLUMIC ACID - NEW TRANSDERMAL ANTI-INFLAMMATORY MEDICINE

The present invention is referred to the encapsulation of the drug Niflumic acid in liposomes with the purpose to create a new transdermal non-steroidal anti-flammatory formulation. The Niflumic acid as well as its ester derivates, have been encapsulated into liposomes with different lipid formulati...

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Hauptverfasser: GEORGOPOULOS ARISTIDIS, TSAMOURIS GEORGIOS, KAMMENOU HELEN, HATZIANTONIOU SOFIA, DEMETZOS KONSTANTINOS, GIANNISIS GEORGIOS, NOUNESIS GEORGIOS, PAPAIOANNOU GEORGIOS, SAVVA-DIMOPOULOU CHRISTINA, RALLIS MICHALIS
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention is referred to the encapsulation of the drug Niflumic acid in liposomes with the purpose to create a new transdermal non-steroidal anti-flammatory formulation. The Niflumic acid as well as its ester derivates, have been encapsulated into liposomes with different lipid formulations in order to achieve the increased effectiveness of the active compound. The liposome suspension, with or without the encapsulated drug has been formulated as a cream and a stability study of the final formulation has followed.