Process for preparing concentrates of aucubin and catalpol from leaves of Plantago species

Concentrate of aucubin and catalpol from leaves of Plantago species is prepared by extracting the leaves in hot water, the extract is then separated by filtration, soluble carbohydrates in the extract are removed by culturing in the presence of microorganisms utilizing monosaccharides and disacchari...

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Hauptverfasser: Štefuca, Vladimír, Višňovský, Jozef, Sitkey, Vladimír, Šutovská Vranková, Kvetoslava, Chochulová, Alžbeta, Dočolomanský, Peter, Rosenberg, Michal
Format: Patent
Sprache:eng ; slo
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Zusammenfassung:Concentrate of aucubin and catalpol from leaves of Plantago species is prepared by extracting the leaves in hot water, the extract is then separated by filtration, soluble carbohydrates in the extract are removed by culturing in the presence of microorganisms utilizing monosaccharides and disaccharides (preferably with yeast Saccharomyces cerevisiae), the cells of microorganisms are removed from the medium after culturing, and aucubin and catalpol are isolated from the separated solution by adsorption on activated carbon. Koncentrát aukubínu a katalpolu z listov rastlín druhu Plantago sa pripravuje extrakciou listov v horúcej vode, extrakt sa následne oddelí filtráciou, rozpustné sacharidy v extrakte sa odstránia kultiváciou v prítomnosti mikroorganizmov utilizujúcich monosacharidy a disacharidy (výhodne pomocou kvasiniek Saccharomyces cerevisiae), po kultivácii sa bunky mikroorganizmov z média odstránia a z oddeleného roztoku sa izolujú aukubín a katalpol pomocou adsorpcie na aktívnom uhlí.