Benzopyran derivatives and pharmaceutical composition containing them
It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group,...
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| creator | MATSUDA TOMOYUKI SHIGETA YUKIHIRO OHRAI KAZUHIKO UESUGI OSAMU OKADA TAKUMI |
| description | It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group, which may be arbitrarily substituted with 1 to 3 R10; C2-4alkyl group; C3-8cycloalkyl group; C3-8cycloalkenyl group which may be arbitrarily substituted with halogen atom, carboxy group or hydroxyl group, R10 is a halogen atom, a hydroxy group or an amino group and the ring structure A is chose from nitrogen heterocycles; pharmaceutical composition comprising said derivative and its use for treating arrhythmia.
It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group, which may be arbitrarily substituted with 1 to 3 R10; C2-4alkyl group; C3-8cycloalkyl group; C3-8cycloalkenyl group which may be arbitrarily substituted with halogen atom, carboxy group or hydroxyl group, R10 is a halogen atom, a hydroxy group or an amino group and the ring structure A is chose from nitrogen heterocycles; pharmaceutical composition comprising said derivative and its use for treating arrhythmia. |
| format | Patent |
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It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group, which may be arbitrarily substituted with 1 to 3 R10; C2-4alkyl group; C3-8cycloalkyl group; C3-8cycloalkenyl group which may be arbitrarily substituted with halogen atom, carboxy group or hydroxyl group, R10 is a halogen atom, a hydroxy group or an amino group and the ring structure A is chose from nitrogen heterocycles; pharmaceutical composition comprising said derivative and its use for treating arrhythmia.</description><language>eng ; slo</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120903&DB=EPODOC&CC=SK&NR=287994B6$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120903&DB=EPODOC&CC=SK&NR=287994B6$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MATSUDA TOMOYUKI</creatorcontrib><creatorcontrib>SHIGETA YUKIHIRO</creatorcontrib><creatorcontrib>OHRAI KAZUHIKO</creatorcontrib><creatorcontrib>UESUGI OSAMU</creatorcontrib><creatorcontrib>OKADA TAKUMI</creatorcontrib><title>Benzopyran derivatives and pharmaceutical composition containing them</title><description>It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group, which may be arbitrarily substituted with 1 to 3 R10; C2-4alkyl group; C3-8cycloalkyl group; C3-8cycloalkenyl group which may be arbitrarily substituted with halogen atom, carboxy group or hydroxyl group, R10 is a halogen atom, a hydroxy group or an amino group and the ring structure A is chose from nitrogen heterocycles; pharmaceutical composition comprising said derivative and its use for treating arrhythmia.
It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group, which may be arbitrarily substituted with 1 to 3 R10; C2-4alkyl group; C3-8cycloalkyl group; C3-8cycloalkenyl group which may be arbitrarily substituted with halogen atom, carboxy group or hydroxyl group, R10 is a halogen atom, a hydroxy group or an amino group and the ring structure A is chose from nitrogen heterocycles; pharmaceutical composition comprising said derivative and its use for treating arrhythmia.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHB1Ss2ryi-oLErMU0hJLcosSyzJLEstVkjMS1EoyEgsyk1MTi0tyUxOzFFIzs8tyC_OLMnMzwOy80oSM_My89IVSjJSc3kYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxAdCQvNSS-GBvIwtzS0sTJyczYyKUAAAaTjQ0</recordid><startdate>20120903</startdate><enddate>20120903</enddate><creator>MATSUDA TOMOYUKI</creator><creator>SHIGETA YUKIHIRO</creator><creator>OHRAI KAZUHIKO</creator><creator>UESUGI OSAMU</creator><creator>OKADA TAKUMI</creator><scope>EVB</scope></search><sort><creationdate>20120903</creationdate><title>Benzopyran derivatives and pharmaceutical composition containing them</title><author>MATSUDA TOMOYUKI ; SHIGETA YUKIHIRO ; OHRAI KAZUHIKO ; UESUGI OSAMU ; OKADA TAKUMI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SK287994BB63</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; slo</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MATSUDA TOMOYUKI</creatorcontrib><creatorcontrib>SHIGETA YUKIHIRO</creatorcontrib><creatorcontrib>OHRAI KAZUHIKO</creatorcontrib><creatorcontrib>UESUGI OSAMU</creatorcontrib><creatorcontrib>OKADA TAKUMI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MATSUDA TOMOYUKI</au><au>SHIGETA YUKIHIRO</au><au>OHRAI KAZUHIKO</au><au>UESUGI OSAMU</au><au>OKADA TAKUMI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Benzopyran derivatives and pharmaceutical composition containing them</title><date>2012-09-03</date><risdate>2012</risdate><abstract>It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group, which may be arbitrarily substituted with 1 to 3 R10; C2-4alkyl group; C3-8cycloalkyl group; C3-8cycloalkenyl group which may be arbitrarily substituted with halogen atom, carboxy group or hydroxyl group, R10 is a halogen atom, a hydroxy group or an amino group and the ring structure A is chose from nitrogen heterocycles; pharmaceutical composition comprising said derivative and its use for treating arrhythmia.
It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group, which may be arbitrarily substituted with 1 to 3 R10; C2-4alkyl group; C3-8cycloalkyl group; C3-8cycloalkenyl group which may be arbitrarily substituted with halogen atom, carboxy group or hydroxyl group, R10 is a halogen atom, a hydroxy group or an amino group and the ring structure A is chose from nitrogen heterocycles; pharmaceutical composition comprising said derivative and its use for treating arrhythmia.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Benzopyran derivatives and pharmaceutical composition containing them |
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