Process of preparing quinazoline compounds and starting compound of this process
The present invention relates to process of preparing quinazoline compounds of the general formula (1) and the pharmaceutically acceptable salts and solvates thereof, as well as structurally related compounds. The foregoing compounds are useful in the treatment of hyperproliferative disorders, such...
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| creator | LEHNER RICHARD SHELTON NORRIS TIMOTHY DINOS PAUL SANTAFIANOS |
| description | The present invention relates to process of preparing quinazoline compounds of the general formula (1) and the pharmaceutically acceptable salts and solvates thereof, as well as structurally related compounds. The foregoing compounds are useful in the treatment of hyperproliferative disorders, such as cancers, in mammals. The subject is also the starting compound of this process.
Vynález sa týka spôsobu prípravy chinazolínovej zlúčeniny všeobecného vzorca (1) a jej farmaceuticky prijateľných solí a solvátov a rovnako štruktúrne príbuzných zlúčenín. Tieto zlúčeniny sú použiteľné pri liečbe hyperproliferačných chorôb, napríklad rakoviny, u cicavcov. Predmetom je i východisková zlúčenina uvedeného spôsobu. |
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Vynález sa týka spôsobu prípravy chinazolínovej zlúčeniny všeobecného vzorca (1) a jej farmaceuticky prijateľných solí a solvátov a rovnako štruktúrne príbuzných zlúčenín. Tieto zlúčeniny sú použiteľné pri liečbe hyperproliferačných chorôb, napríklad rakoviny, u cicavcov. Predmetom je i východisková zlúčenina uvedeného spôsobu.</description><language>eng ; slo</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; AGRICULTURE ; ANIMAL HUSBANDRY ; APPARATUS THEREFOR ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; CHEMISTRY ; FERROUS OR NON-FERROUS ALLOYS ; FISHING ; FORESTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HUNTING ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; PRETREATMENT OF RAW MATERIALS ; PRODUCTION AND REFINING OF METALS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; TRAPPING ; TREATMENT OF ALLOYS OR NON-FERROUS METALS</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100707&DB=EPODOC&CC=SK&NR=287339B6$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100707&DB=EPODOC&CC=SK&NR=287339B6$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEHNER RICHARD SHELTON</creatorcontrib><creatorcontrib>NORRIS TIMOTHY</creatorcontrib><creatorcontrib>DINOS PAUL SANTAFIANOS</creatorcontrib><title>Process of preparing quinazoline compounds and starting compound of this process</title><description>The present invention relates to process of preparing quinazoline compounds of the general formula (1) and the pharmaceutically acceptable salts and solvates thereof, as well as structurally related compounds. The foregoing compounds are useful in the treatment of hyperproliferative disorders, such as cancers, in mammals. The subject is also the starting compound of this process.
Vynález sa týka spôsobu prípravy chinazolínovej zlúčeniny všeobecného vzorca (1) a jej farmaceuticky prijateľných solí a solvátov a rovnako štruktúrne príbuzných zlúčenín. Tieto zlúčeniny sú použiteľné pri liečbe hyperproliferačných chorôb, napríklad rakoviny, u cicavcov. Predmetom je i východisková zlúčenina uvedeného spôsobu.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>APPARATUS THEREFOR</subject><subject>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</subject><subject>CHEMISTRY</subject><subject>FERROUS OR NON-FERROUS ALLOYS</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>GENERAL METHODS OF ORGANIC CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEST REPELLANTS OR ATTRACTANTS</subject><subject>PLANT GROWTH REGULATORS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</subject><subject>PRETREATMENT OF RAW MATERIALS</subject><subject>PRODUCTION AND REFINING OF METALS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>TRAPPING</subject><subject>TREATMENT OF ALLOYS OR NON-FERROUS METALS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAgIKMpPTi0uVshPUygoSi1ILMrMS1coLM3MS6zKz8nMS1VIzs8tyC_NSylWSMxLUSguSSwqASmBCYM0lmRkFgN1gw3iYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxwd5GFubGxpZOTmbGRCgBAJOkN_Q</recordid><startdate>20100707</startdate><enddate>20100707</enddate><creator>LEHNER RICHARD SHELTON</creator><creator>NORRIS TIMOTHY</creator><creator>DINOS PAUL SANTAFIANOS</creator><scope>EVB</scope></search><sort><creationdate>20100707</creationdate><title>Process of preparing quinazoline compounds and starting compound of this process</title><author>LEHNER RICHARD SHELTON ; NORRIS TIMOTHY ; DINOS PAUL SANTAFIANOS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SK287339BB63</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; slo</language><creationdate>2010</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>APPARATUS THEREFOR</topic><topic>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</topic><topic>CHEMISTRY</topic><topic>FERROUS OR NON-FERROUS ALLOYS</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>GENERAL METHODS OF ORGANIC CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEST REPELLANTS OR ATTRACTANTS</topic><topic>PLANT GROWTH REGULATORS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</topic><topic>PRETREATMENT OF RAW MATERIALS</topic><topic>PRODUCTION AND REFINING OF METALS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>TRAPPING</topic><topic>TREATMENT OF ALLOYS OR NON-FERROUS METALS</topic><toplevel>online_resources</toplevel><creatorcontrib>LEHNER RICHARD SHELTON</creatorcontrib><creatorcontrib>NORRIS TIMOTHY</creatorcontrib><creatorcontrib>DINOS PAUL SANTAFIANOS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEHNER RICHARD SHELTON</au><au>NORRIS TIMOTHY</au><au>DINOS PAUL SANTAFIANOS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Process of preparing quinazoline compounds and starting compound of this process</title><date>2010-07-07</date><risdate>2010</risdate><abstract>The present invention relates to process of preparing quinazoline compounds of the general formula (1) and the pharmaceutically acceptable salts and solvates thereof, as well as structurally related compounds. The foregoing compounds are useful in the treatment of hyperproliferative disorders, such as cancers, in mammals. The subject is also the starting compound of this process.
Vynález sa týka spôsobu prípravy chinazolínovej zlúčeniny všeobecného vzorca (1) a jej farmaceuticky prijateľných solí a solvátov a rovnako štruktúrne príbuzných zlúčenín. Tieto zlúčeniny sú použiteľné pri liečbe hyperproliferačných chorôb, napríklad rakoviny, u cicavcov. Predmetom je i východisková zlúčenina uvedeného spôsobu.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM AGRICULTURE ANIMAL HUSBANDRY APPARATUS THEREFOR BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FERROUS OR NON-FERROUS ALLOYS FISHING FORESTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PRETREATMENT OF RAW MATERIALS PRODUCTION AND REFINING OF METALS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRAPPING TREATMENT OF ALLOYS OR NON-FERROUS METALS |
| title | Process of preparing quinazoline compounds and starting compound of this process |
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