Devices for the controlled release of drugs having antiprogestinic properties

Devices for the controlled release of drugs, having antiprogestinic properties, over a prolonged period of time, wherein said devises comprising a core comprising the drug, optionally a membrane encasing the core, wherein the core and membrane is made of a siloxane-based elastomer composition compri...

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Hauptverfasser: RUOHONEN JARKKO, ALA-SORVARI JUHA, LEHTINEN MATTI, HAAPAKUMPU TIMO, MARKKULA TOMMI, JUKARAINEN HARRI
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creator RUOHONEN JARKKO
ALA-SORVARI JUHA
LEHTINEN MATTI
HAAPAKUMPU TIMO
MARKKULA TOMMI
JUKARAINEN HARRI
description Devices for the controlled release of drugs, having antiprogestinic properties, over a prolonged period of time, wherein said devises comprising a core comprising the drug, optionally a membrane encasing the core, wherein the core and membrane is made of a siloxane-based elastomer composition comprising at least one elastomer and possibly non-crosslinked polymer. The elastomer composition comprising poly(alkylene oxide) groups present in the elastomer, or polymer in the form of alkoxy-terminated grafts of polysiloxane units, or as the blocks, the grafts being linked to the polysiloxane units by silicon-carbon bond, or as a mixture of these forms. Prostriedky na kontrolované uvoľňovanie látok, majúcich antiprogestínové vlastnosti, počas dlhšieho časového obdobia, kde uvedené prostriedky zahrnujú jadro obsahujúce liek, prípadne membránu obaľujúcu toto jadro, kde jadro a membrána sú vyrobené z na siloxáne založenej elastomérnej kompozícii obsahujúcej aspoň jeden elastomér a prípadne nesieťovaný polymér. Elastomérna kompozícia obsahuje polyalkylénoxidové skupiny prítomné v elastoméri, alebo polyméri vo forme ako alkoxy zakončené štepy polysiloxánových jednotiek, alebo ako bloky, uvedené štepy, alebo bloky sú pripojené na polysiloxánové jednotky väzbou uhlík-kremík, alebo ako zmes týchto foriem.
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR CHEMICAL WORKING-UP
title Devices for the controlled release of drugs having antiprogestinic properties
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