Devices for the controlled release of drugs having antiprogestinic properties

Devices for the controlled release of drugs, having antiprogestinic properties, over a prolonged period of time, wherein said devises comprising a core comprising the drug, optionally a membrane encasing the core, wherein the core and membrane is made of a siloxane-based elastomer composition compri...

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Hauptverfasser:	RUOHONEN JARKKO, ALA-SORVARI JUHA, LEHTINEN MATTI, HAAPAKUMPU TIMO, MARKKULA TOMMI, JUKARAINEN HARRI
Format:	Patent
Sprache:	eng ; slo
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	Devices for the controlled release of drugs, having antiprogestinic properties, over a prolonged period of time, wherein said devises comprising a core comprising the drug, optionally a membrane encasing the core, wherein the core and membrane is made of a siloxane-based elastomer composition comprising at least one elastomer and possibly non-crosslinked polymer. The elastomer composition comprising poly(alkylene oxide) groups present in the elastomer, or polymer in the form of alkoxy-terminated grafts of polysiloxane units, or as the blocks, the grafts being linked to the polysiloxane units by silicon-carbon bond, or as a mixture of these forms. Prostriedky na kontrolované uvoľňovanie látok, majúcich antiprogestínové vlastnosti, počas dlhšieho časového obdobia, kde uvedené prostriedky zahrnujú jadro obsahujúce liek, prípadne membránu obaľujúcu toto jadro, kde jadro a membrána sú vyrobené z na siloxáne založenej elastomérnej kompozícii obsahujúcej aspoň jeden elastomér a prípadne nesieťovaný polymér. Elastomérna kompozícia obsahuje polyalkylénoxidové skupiny prítomné v elastoméri, alebo polyméri vo forme ako alkoxy zakončené štepy polysiloxánových jednotiek, alebo ako bloky, uvedené štepy, alebo bloky sú pripojené na polysiloxánové jednotky väzbou uhlík-kremík, alebo ako zmes týchto foriem.