Phenyl- and pyridyl- tetrahydro-pyridines, method for preparing and pharmaceutical composition containing them and use thereof
It is described compounds of formula (I) wherein: X represents N or CH; R1 represents a hydrogen or halogen atom, or a CF3 group; R2 and R3 independently represent a hydrogen atom or a methyl group; n is 0 or 1; A represents a group of formula (a) or (b) wherein: R4 represents a hydrogen or halogen...
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Format: | Patent |
Sprache: | eng ; slo |
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Zusammenfassung: | It is described compounds of formula (I) wherein: X represents N or CH; R1 represents a hydrogen or halogen atom, or a CF3 group; R2 and R3 independently represent a hydrogen atom or a methyl group; n is 0 or 1; A represents a group of formula (a) or (b) wherein: R4 represents a hydrogen or halogen atom, a C1-C4 alkyl group, a CF3 group, an amino, mono(C1-C4)alkylamino, di(C1-C4)alkylamino; R5 represents a hydrogen or halogen atom, a (C1-C4)alkoxy group, a (C1-C4)alkyl group or a CF3 group; R6 represents a hydrogen atom, a (C1-C4)alkyl group or a (C1-C4)alkoxy group; and their salts or solvates, pharmaceutical compositions containing them, a method for preparing them and the synthesis intermediates in said method.
Opisujú sa zlúčeniny vzorca (I), kde X je N alebo CH; R1 je vodík alebo halogén, alebo CF3; R2 a R3 sú vodík alebo metyl; n je 0 alebo 1; A je skupina (a) alebo (b), kde R4 je vodík alebo halogén, C1-4alkyl, CF3, aminoskupina, monoC1-4alkylaminoskupina, diC1-4alkylaminoskupina; R5 je vodík alebo halogén, C1-4alkoxyskupina, C1-4alkyl alebo CF3; R6 je vodík, C1-4alkyl alebo C1-4alkoxyskupina; a ich soli alebo solváty, farmaceutické kompozície, ktoré ich obsahujú, spôsoby ich prípravy a prípravy medziproduktov na tieto spôsoby a použitie. |
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