PYRIDINYL-AMINOMETHYLIDENE BIPHOSPHONIC ACID TETRAESTERS, PHARMAC EUTICAL PREPARATION CONTAINING THEM AND THEIR USE

Pyridinyl-aminomethylidene biphosphonic acid tetraesters of general formula (I) with the meaning of substituents listed in the claim 1, which are optionally substituted on the pyridine ring, are the active substance of the pharmaceutical preparation and are used for treatment of bone diseases such a...

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Hauptverfasser: KLEIMOLA TERTTU, SELLMAN RAIJA, HEIKKILA-HOIKKA MARJAANA, VAANANEN KALERVO, NIKANDER HANNU, LIUKKO-SIPI SIRPA, HANNUNIEMI RITVA, LAUREN LEENA
Format: Patent
Sprache:eng ; slo
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Zusammenfassung:Pyridinyl-aminomethylidene biphosphonic acid tetraesters of general formula (I) with the meaning of substituents listed in the claim 1, which are optionally substituted on the pyridine ring, are the active substance of the pharmaceutical preparation and are used for treatment of bone diseases such as osteolytic bone diseases of the malignant exuberance, Paget's disease and primary and secondary osteoporosis. Tetraestery kyseliny pyridinyl-aminometylidénbisfosfónovej všeobecného vzorca (I) s významom substituentov uvedených v nároku 1, ktoré sú prípadne substituované na pyridínovom kruhu, sú účinnou látkou farmaceutického prostriedku a používajú sa pri liečení kostných ochorení, ako sú osteolytické kostné ochorenia zhubného bujnenia, Pagetova choroba a primárna a sekundárna osteoporóza.ŕ