SYNTHETIC EXCITATORY AMINO ACIDS, PREPARATION METHOD THEREOF, INTERMEDIATES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

SYNTHETIC EXCITATORY AMINO ACIDS, PREPARATION METHOD THEREOF, INTERMEDIATES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Zlúčeniny všeobecného vzorca (I), v ktorom X je (CH2)n, pričom n je 1; R2 je CO2R4 a R3 je vodík alebo R2 je vodík a R3 je CO2R4; R1 a R4 sú nezávisle vodík, C1-10alkyl, C2-10alkenyl, aryl alebo arylalkyl alebo ich farmaceuticky prijateľné soli; spôsob ich prípravy; medziprodukt na ich prípravu a fa...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MONN JAMES ALLEN, SCHOEPP DARRYLE DARWIN, HELTON DAVID REED
Format: Patent
Sprache:eng ; slo
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Zlúčeniny všeobecného vzorca (I), v ktorom X je (CH2)n, pričom n je 1; R2 je CO2R4 a R3 je vodík alebo R2 je vodík a R3 je CO2R4; R1 a R4 sú nezávisle vodík, C1-10alkyl, C2-10alkenyl, aryl alebo arylalkyl alebo ich farmaceuticky prijateľné soli; spôsob ich prípravy; medziprodukt na ich prípravu a farmaceutický prostriedok s ich obsahom.ŕ The present invention provides novel compounds that affect certain excitatory amino acid receptors, and are useful in the treatment of neurological disorders and psychiatric disorders. The compounds have the formula wherein: X is (CH2)n; R is CO2R and R is hydrogen, or R is hydrogen and R is CO2R ; R and R are independently hydrogen, C1-C10 alkyl, C2-C10 alkenyl, aryl, or arylalkyl; and n is 1; or a pharmaceutically-acceptable salt thereof. cer