USE OF 5-THIA-1,4-DIAZABICYCLO[4.2.0]OCTANE-3,8-DIOXO COMPOUNDS IN ANTITUMOR THERAPY

The present invention relates to the use of 5-thia-1,4-diazabicyclo[4.2.0]octane-3,8-dioxo compounds of the general formula (I), wherein R1 is hydrogen or halogen; R2 is hydrogen, halogen, amino, and the others; R is hydrogen, alkyl, benzyl, a heterocyclic ring; and n is 1 or 2, which compounds are...

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Hauptverfasser: GRDISA MIRA, HORVATIC MARJETA, HERAK JURE J, PAVELIC KRESIMIR, MANDIC ZORA, TOMIC MIRJANA, KOVACEVIC MICE, LUKIC IRENA
Format: Patent
Sprache:eng ; slo
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Zusammenfassung:The present invention relates to the use of 5-thia-1,4-diazabicyclo[4.2.0]octane-3,8-dioxo compounds of the general formula (I), wherein R1 is hydrogen or halogen; R2 is hydrogen, halogen, amino, and the others; R is hydrogen, alkyl, benzyl, a heterocyclic ring; and n is 1 or 2, which compounds are usable in the suppression of uterine cervix carcinoma cells. Použitie 5-tia-1,4-diazabicyklo[4.2.0]oktán-3,8- -dioxozlúčenín všeobecného vzorca (I), v ktorom R1 je vodík alebo halogén; R2 znamená napríklad atóm vodíka, atóm halogénu, aminoskupinu a iné; R3 je vodík, alkyl, benzyl alebo heterocyklický kruh a n je 1 alebo 2, ako účinných látok farmaceutických prostriedkov určených na potlačenie rastu buniek rakoviny krčka maternice.ŕ