8-SUBSTITUTED-2-AMINOTETRALINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE

A compound of formula (I), where Z is hydrogen or halogen, Q is COR1 or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis-configuration), R1 is C1-C6 alkyl or an aromatic ring which may contain h...

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Bibliographische Detailangaben
Hauptverfasser:	BACKLUND HOOK BERIT CHRISTINA ELISABET, HACKSELL ULI ALF, ANDEN NILS-ENRIK, MELLIN EVA CHARLOTTA, YU HONG, BJORK ANNA LENA MARIA, HILLVER SVEN-ERIK, LIU YE, PERSSON EVA MARIE, VALLGARDA KARL JERK
Format:	Patent
Sprache:	eng ; slo
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A compound of formula (I), where Z is hydrogen or halogen, Q is COR1 or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis-configuration), R1 is C1-C6 alkyl or an aromatic ring which may contain heteroatoms selected from O and S and may be substituted or fused to an optionally substituted benzene ring, R2 is hydrogen or C1-C6 alkyl and R3 may be different groups defined in claim 1, and enantiomers/salts thereof, processes for preparation of said compounds, pharmaceutical preparations containing said compounds, use of and method of treatment of disorders in CNS by using said compounds.