PROCESS FOR THE PRODUCTION OF 7-AMINODESACETOXYCEPHALOSPORANIC ACID VIA EXPANDASE ACTIVITY ON PENICILLIN G

An overall process for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G, using a Penicillium chrysogenum transformant strain expressing expandase.

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Hauptverfasser: SCHIPPER DIRK, KOEKMAN BERTUS P, BOVENBERG ROELOF A. L, VOLLEBREGT ADRIANUS W. H
Format: Patent
Sprache:eng ; slo
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Zusammenfassung:An overall process for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G, using a Penicillium chrysogenum transformant strain expressing expandase.