ANTIVIRALLY ACTIVE PHARMACEUTICAL EMULSION

An antivirally active pharmaceutical oil-in-water emulsion containing glycerol formal as an organic solvent in the continuous aqueous phase in stead of a polyhydroxylic alcohol or glycerol formal as a substitution for a part of said polyhydroxylic alcohol, said emulsion contains a higher concentrati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	LISSAU BODIL G, BJORNSDOTTIR KAREN, PEDERSEN SOREN B, ALHEDE BORGE I. F, GEBHARD-HANSEN KNUD E
Format:	Patent
Sprache:	eng ; slo
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	An antivirally active pharmaceutical oil-in-water emulsion containing glycerol formal as an organic solvent in the continuous aqueous phase in stead of a polyhydroxylic alcohol or glycerol formal as a substitution for a part of said polyhydroxylic alcohol, said emulsion contains a higher concentration of 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof. A higher transdermal penetration can be achieved when using said emulsion. The emulsion is available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.