PARMACEUTICAL LYOPHILIZATE COMPOSITIONS BASED ON IFOSFAMIDE WITH INCRESED STABILITY AND PROCESS FOR PREPARING THEREOF

PARMACEUTICAL LYOPHILIZATE COMPOSITIONS BASED ON IFOSFAMIDE WITH INCRESED STABILITY AND PROCESS FOR PREPARING THEREOF

Improved lyophilizate compositions of ifosfamide comprising urea as the primary excipient and, optionally, sodium 2-mercaptoethanesulfonate (mesna), are produced in a modified freeze-drying process to give products with increased heat stability and extended shelf storage life.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SCOTT JOSEPH A, BEHME ROBERT J, BROOKE DANA, ALEXANDER ROBERT L
Format: Patent
Sprache:eng ; slo
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Improved lyophilizate compositions of ifosfamide comprising urea as the primary excipient and, optionally, sodium 2-mercaptoethanesulfonate (mesna), are produced in a modified freeze-drying process to give products with increased heat stability and extended shelf storage life.