HIGH-PRODUCTIVE STRAIN OF PENICILLIUM CHRYSOGENUM CCM MICROORGANISM

This patent describes the micro-organism strain called Penicillium chrysogenum CCM 8197 (NMG-FOOK 31) able to reach a high level of the production. This micro-organism strain was gained based on the selection of mutants created when acting mutagens and phenoxy-acetic acid to the spore at the submers...

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Hauptverfasser: BUCKO MICHAL, LICHY MILOS, DURANOVA VIERA, BOROSOVA GABRIELA, LUCINA DUSAN, KLUKA LUBOMIR, RAKYTA JAN, KOSC PAVEL
Format: Patent
Sprache:eng ; slo
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Zusammenfassung:This patent describes the micro-organism strain called Penicillium chrysogenum CCM 8197 (NMG-FOOK 31) able to reach a high level of the production. This micro-organism strain was gained based on the selection of mutants created when acting mutagens and phenoxy-acetic acid to the spore at the submersion cultivation. As a result of the subsequent passive selection, the strain called Penicillium chrysogenum CCM 8197 (NMG FOOK 31) producing more than 35 000 IU PEN V/ml for 168 hours of cultivation was gained in the flasks, at the temperature of 25 Celsius degrees, when flowing air simultaneously.