THERMOPLASTIC FOR DRUG COVERS PRODUCTION, MANUFACTURING PROCESS AND USE THEREOF

Thermoplastic materials (I) for prodn. of pharmaceutical capsules that are soluble in intestinal fluid comprise a copolymer of 16-40 wt.% acrylic acid (AA) and/or methacrylic acid (MAA), 30-80 wt.% methyl acrylate (MA) and 0-40 wt.% of other alkyl (meth)acrylates, opt. together with conventional pha...

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Hauptverfasser: HOES WERNER, LEHMANN KLAUS
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LEHMANN KLAUS
description Thermoplastic materials (I) for prodn. of pharmaceutical capsules that are soluble in intestinal fluid comprise a copolymer of 16-40 wt.% acrylic acid (AA) and/or methacrylic acid (MAA), 30-80 wt.% methyl acrylate (MA) and 0-40 wt.% of other alkyl (meth)acrylates, opt. together with conventional pharmaceutical coating additives. (I) are insoluble at pH values below 5.5 and soluble at pH 5.5-8. They can be melt-processed at 140-180 degrees C without loss of solubility in intestinal fluid.
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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
title THERMOPLASTIC FOR DRUG COVERS PRODUCTION, MANUFACTURING PROCESS AND USE THEREOF
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