THERMOPLASTIC FOR DRUG COVERS PRODUCTION, MANUFACTURING PROCESS AND USE THEREOF

THERMOPLASTIC FOR DRUG COVERS PRODUCTION, MANUFACTURING PROCESS AND USE THEREOF

Thermoplastic materials (I) for prodn. of pharmaceutical capsules that are soluble in intestinal fluid comprise a copolymer of 16-40 wt.% acrylic acid (AA) and/or methacrylic acid (MAA), 30-80 wt.% methyl acrylate (MA) and 0-40 wt.% of other alkyl (meth)acrylates, opt. together with conventional pha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HOES WERNER, LEHMANN KLAUS
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
COMPOSITIONS BASED THEREON
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:Thermoplastic materials (I) for prodn. of pharmaceutical capsules that are soluble in intestinal fluid comprise a copolymer of 16-40 wt.% acrylic acid (AA) and/or methacrylic acid (MAA), 30-80 wt.% methyl acrylate (MA) and 0-40 wt.% of other alkyl (meth)acrylates, opt. together with conventional pharmaceutical coating additives. (I) are insoluble at pH values below 5.5 and soluble at pH 5.5-8. They can be melt-processed at 140-180 degrees C without loss of solubility in intestinal fluid.