8-CYANO-5-PIPERIDINO-QUINOLINES AS TLR7/8 ANTAGONISTS AND THEIR USES FOR TREATING IMMUNE DISORDERS

8-CYANO-5-PIPERIDINO-QUINOLINES AS TLR7/8 ANTAGONISTS AND THEIR USES FOR TREATING IMMUNE DISORDERS

The invention relates to the cis racemic, cis isomer 1 and cis isomer 2 forms of following compound, useful as TLR7/8 antagonists for treating e.g. systemic lupus erythematosus, and to pharmaceutically acceptable compositions thereof.

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Bibliographische Detailangaben
Hauptverfasser: Sherer Brian, Brugger Nadia
Format: Patent
Sprache:eng ; slv
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to the cis racemic, cis isomer 1 and cis isomer 2 forms of following compound, useful as TLR7/8 antagonists for treating e.g. systemic lupus erythematosus, and to pharmaceutically acceptable compositions thereof.