BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS

The present invention encompasses compounds of formula (I)wherein the groups R1 to R4, A and p have the meanings given in the claims and specification, their use as inhibitors of SOS1, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especia...

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Hauptverfasser: GILLE Annika, WUNBERG Tobias, RUDOLPH Dorothea Ingrid, GOEPPER Stefan, RAMHARTER Juergen, BAUM Anke, SAVARESE Fabio, STADTMUELLER Heinz, SANTAGOSTINO Marco, GMACHL Michael, HOFMANN Marco Hans, FRANK Markus, WIPPICH Julian, KOFINK Christiane, OSTERMEIER Markus
Format: Patent
Sprache:eng ; slv
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Zusammenfassung:The present invention encompasses compounds of formula (I)wherein the groups R1 to R4, A and p have the meanings given in the claims and specification, their use as inhibitors of SOS1, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.