NAPHTHYRIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ARRHYTHMIA

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof:wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of phar...

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Bibliographische Detailangaben
Hauptverfasser: PEUKERT Stefan, BARBE Guillaume, BEBERNITZ Gregory Raymond, PARKER David Thomas, LIAO Lv, PENG Yunshan, GULGEZE EFTHYMIOU Hatice Belgin, GENG Sicong, MA Fupeng, YAMADA Ken, SMITH Nichola, YASOSHIMA Kayo, MO Ruowei
Format: Patent
Sprache:eng ; slv
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Zusammenfassung:The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof:wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.