CANCER CELL BINDING RECOMBINANT LECTINS WITH ANTITUMOR ACTIVITY AND METHOD OF PREPARATION

CANCER CELL BINDING RECOMBINANT LECTINS WITH ANTITUMOR ACTIVITY AND METHOD OF PREPARATION

The present invention discloses genes for new variants in E.coli that are more close to the wild type lectin sequence but still differ in surface charges. This recombinant version (exemplified Rec-2 and Rec-3) are cancer cell binding with anti tumor activity show blood group specificity similar to t...

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Hauptverfasser: CHACHADI Vishwanath Basavaraj, RAMADOSS Candadai Seshadri, SWAMY Bale Murugi, VENKAT Hemalatha, INAMDAR Shashikala Ramchandra, NAGRE Nagaraja Narayan
Format: Patent
Sprache:eng ; slv
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Zusammenfassung:The present invention discloses genes for new variants in E.coli that are more close to the wild type lectin sequence but still differ in surface charges. This recombinant version (exemplified Rec-2 and Rec-3) are cancer cell binding with anti tumor activity show blood group specificity similar to the native lectin but retains the stability and the solubility properties.