METHOD FOR THE PRODUCTION OF FREEZE-DRIED PELLETS COMPRISING FACTOR VIII

A method for the production of freeze-dried pellets comprising factor VIII comprises the steps of: a) freezing droplets of a solution comprising factor VIII to form pellets; b) freeze-drying the pellets; wherein in step a) the droplets are formed by means of droplet formation of the solution compris...

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Bibliographische Detailangaben
Hauptverfasser:	OLBRICH Carsten, SCHNEID Stefan Christian, LUY Bernhard, PLITZKO Matthias
Format:	Patent
Sprache:	eng ; slv
Schlagworte:	BLASTING CHEMISTRY DRYING DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM HEATING HUMAN NECESSITIES HYGIENE LIGHTING MECHANICAL ENGINEERING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES WEAPONS
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Beschreibung
Zusammenfassung:	A method for the production of freeze-dried pellets comprising factor VIII comprises the steps of: a) freezing droplets of a solution comprising factor VIII to form pellets; b) freeze-drying the pellets; wherein in step a) the droplets are formed by means of droplet formation of the solution comprising factor VIII into a cooling tower which has a temperature-controllable inner wall surface and an interior temperature below the freezing temperature of the solution and wherein in step b) the pellets are freeze-dried in a rotating receptacle which is housed inside a vacuum chamber.