PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII

The present invention provides compounds of formula (I)wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising...

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Bibliographische Detailangaben
Hauptverfasser:	SHEN Hong, WAHHAB Amal, HU Taishan, THOMAS Helmut, SCHAEUBLIN Adrian, ALANINE Alexander, KROLL Carsten, JACKSON Stephen, MACDONALD Dwight, ZAMPALONI Claudia, BLEICHER Konrad, KOLCZEWSKI Sabine, BEIGNET Julien, STOLL Theodor, HILPERT Hans, FASCHING Bernhard
Format:	Patent
Sprache:	eng ; slv
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds of formula (I)wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.