MODIFIED NUCLEOTIDES FOR POLYNUCLEOTIDE SEQUENCING

MODIFIED NUCLEOTIDES FOR POLYNUCLEOTIDE SEQUENCING

The invention provides a kit comprising four modified nucleotide triphosphate molecules, each comprising a purine or pyrimidine base and a deoxyribose sugar moiety wherein the 3' carbon atom of the sugar moiety has attached a group of the structure         -O-Zwherein Z is of the formula -CH2N3...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Barnes Colin, Milton John, Wu Xiaolin, Brennan Joseph, Ruediger Silke, Liu Xiaohai, Smith Mark
Format: Patent
Sprache:eng ; slv
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PHYSICS
SUGARS
TESTING
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Beschreibung
Zusammenfassung:The invention provides a kit comprising four modified nucleotide triphosphate molecules, each comprising a purine or pyrimidine base and a deoxyribose sugar moiety wherein the 3' carbon atom of the sugar moiety has attached a group of the structure         -O-Zwherein Z is of the formula -CH2N3.