PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME

The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates, as well as methods for making the conjugates and compositions. The invention further provides met...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WOO Sungho, KIM Sunyoung, KIM Yongzu, PARK Taekyo, LEE Hyangsook, CHO Jongun, OH Kyuman, CHUNG Yunseo, KIM Youngun, JUNG Doohwan, KWON Hyunjin, PARK Yun-hee
Format: Patent
Sprache:eng ; slv
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Zusammenfassung:The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates, as well as methods for making the conjugates and compositions. The invention further provides methods for using the conjugates to deliver the active agent to a target cell, as well as methods for using the conjugates to treat a subject in need thereof (e.g., a subject in need of the active agent).