METHOD OF PREPARAING ENTERIC HARD CAPSULE AND ENTERIC HARD CAPSULE PREPARED THEREBY

A method of preparing enteric hard capsules, and an enteric hard capsule prepared by the method. The method may include: dissolving an enteric base material, a capsule forming aid, and a neutralizing agent in water at room temperature to prepare an aqueous composition; heating the aqueous compositio...

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Bibliographische Detailangaben
Hauptverfasser: BAEK Hyon Ho, SON Jin Ryul, LEE Sung Wan, CHA Jae Uk, SONG Min Gyu, KO Won Hwa, PARK Eun Hee, CHA Ja Hyun
Format: Patent
Sprache:eng ; slv
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Beschreibung
Zusammenfassung:A method of preparing enteric hard capsules, and an enteric hard capsule prepared by the method. The method may include: dissolving an enteric base material, a capsule forming aid, and a neutralizing agent in water at room temperature to prepare an aqueous composition; heating the aqueous composition to a first temperature that is higher than a gelation start temperature of the aqueous composition; cooling the heated aqueous composition to a second temperature that is lower than the gelation start temperature; immersing a mold pin heated to a third temperature that is higher than the gelation start temperature into the aqueous composition; removing the mold pin from the aqueous composition to obtain a film coated on the mold pin; maintaining the film on the mold pin at a fourth temperature that is higher than the gelation start temperature for a first time period to fix the film onto the mold pin; and drying the fixed film at a fifth temperature for a second time period to obtain a capsule shell.