DOSAGE FORMS OF APIXABAN

The present invention provides a process for producing a solid amorphous dispersion of apixaban comprising dissolving apixaban and one or more polymers in a solvent, which dissolves both apixaban and the one or more polymers and removing the solvent by spray drying; a solid amorphous dispersion prep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	NAUSE Richard G
Format:	Patent
Sprache:	eng ; slv
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a process for producing a solid amorphous dispersion of apixaban comprising dissolving apixaban and one or more polymers in a solvent, which dissolves both apixaban and the one or more polymers and removing the solvent by spray drying; a solid amorphous dispersion prepared according to the process; as well as a dosage form comprising the solid amorphous dispersion.