Pyrimidine derivatives used as pi-3 kinase inhibitors

Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; in the prophylaxis or treatment of proliferative diseases characterized by the abnormal acti...

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Hauptverfasser:	BURGER MATTHEW, FRAZIER KELLY, KNAPP MARK, XIN XIAHUA, LOUIE ALICIA, POON DANIEL, IWANOWICZ EDWIN, SMITH AARON, NG SIMON, VOLIVA CHARLES, HENDRICKSON THOMAS, MERITT HANNE, PICK TERESA, WAGMAN ALLAN, BARTULIS SARAH, VERHAGEN JOELLE, NI ZHI-JIE, PECCHI SABINA, BARSANTI PAUL, PFISTER KEITH, WIESMANN MARION, FANTL WENDY, ATALLAH GORDANA, ZHANG YANCHEN
Format:	Patent
Sprache:	eng ; slv
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.