Diaryl ethers as opioid receptor antagonist

A compound of the formula (I) wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obe...

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Hauptverfasser: DE LA TORRE MARTA GARCIA, HOLLOWAY WILLIAM GLEN, CHAPPELL MARK DONALD, STUCKY RUSSELL DEAN, WOLFE CHAD NOLAN, MITCH CHARLES HOWARD, QUIMBY STEVEN JAMES, TAKEUCHI KUMIKO, SIEGEL MILES GOODMAN, FRITZ JAMES ERWIN, DIAZ BUEZO NURIA, SMITH DANA RAE, MATT JAMES EDWARD JUNIOR, BLANCO-PILLADO MARIA-JESUS, PEDREGAL-TERCERO CONCEPCION, THOMAS ELIZABETH MARIE
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Sprache:eng ; slv
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Zusammenfassung:A compound of the formula (I) wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.