Solid pharmaceutical composition comprising valsartan

This invention relates to a solid pharmaceutical composition containing valsartan particles characterized in that the D 50 of said valsartan particles is 150 µm or below and that the valsartan particles have a maximum diameter of no more than 1100 µm, as determined by electron microscopy, and that i...

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Bibliographische Detailangaben
Hauptverfasser: CERNOSA LIDIJA, ZUPANCIC SILVO, RANGUS MARIJA, BEVEC FRANCI, VRBINC MIHA, SLANC VOVK JANIKA
Format: Patent
Sprache:eng ; slv
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Beschreibung
Zusammenfassung:This invention relates to a solid pharmaceutical composition containing valsartan particles characterized in that the D 50 of said valsartan particles is 150 µm or below and that the valsartan particles have a maximum diameter of no more than 1100 µm, as determined by electron microscopy, and that it comprises 30-70 wt.-% of valsartan, 10-70 wt.-% of a diluent, 1-20 wt.-% of a disintegrant, 1-20 wt.-% of a binder and 1-10% of a lubricant, wherein the disintegrant is carboxymethylcellulose sodium.