SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ONCE DAILY DOSING CONTAINING PREGABALIN, A MATRIX FORMING AGENT AND A SWELLING AGENT

A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplar...

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Hauptverfasser: BOCKBRADER HOWARD NORMAN, WAN JIANSHENG, REYNOLDS THOMAS DANIEL, DIAZ SANTIAGO STEVEN, MAHJOUR MAJID, SHAO PUSHPA GANAPATHI, CHO YUN HYUNG, SHAO ZEZHI JESSE
Format: Patent
Sprache:eng ; slv
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Zusammenfassung:A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone.