A METHOD OF WEAK PARTITIONING CHROMATOGRAPHY

This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bin...

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Hauptverfasser: BOOTH James Edward, SWITZER Mary Beth, KELLEY Brian D, BROWN Paul, SUN Shujun, COFFMAN Jon, YU Tianning, GODAVARTI Ranganathan, VUNNUM Suresh, ISKRA Tim
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creator BOOTH James Edward
SWITZER Mary Beth
KELLEY Brian D
BROWN Paul
SUN Shujun
COFFMAN Jon
YU Tianning
GODAVARTI Ranganathan
VUNNUM Suresh
ISKRA Tim
description This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
title A METHOD OF WEAK PARTITIONING CHROMATOGRAPHY
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