A METHOD OF WEAK PARTITIONING CHROMATOGRAPHY

A METHOD OF WEAK PARTITIONING CHROMATOGRAPHY

This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BOOTH James Edward, SWITZER Mary Beth, KELLEY Brian D, BROWN Paul, SUN Shujun, COFFMAN Jon, YU Tianning, GODAVARTI Ranganathan, VUNNUM Suresh, ISKRA Tim
Format: Patent
Sprache:eng ; slv
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
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Beschreibung
Zusammenfassung:This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.