3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

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Bibliographische Detailangaben
Hauptverfasser:	LI GE, FERREIRA JOHAN A, MERRITT ROBERT J, CHAO JIANHUA, TAVERAS ARTHUR G, KAISER BERND, YU YOUNONG, CHAO JIANPING, NELSON KINGSLEY H, DWYER MICHAEL, ROKOSZ LAURA L, BOND RICHARD W, AKI CYNTHIA J, BALDWIN JOHN J
Format:	Patent
Sprache:	eng ; slv
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.