PELLETS CONTAINING VENLAFAXINE HYDROCHLORIDE

The invention relates to pellets containing venlafaxine hydrochloride and a process for the preparation thereof. The pellets according to the invention are nearly spherical in shape and comprise pharmaceutically active venlafaxine hydro­chloride in an amount of at most 80 % by weight, furthermore 10...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FEKETE PAL, KORBELY TIBOR, MORICZ ESZTER, BOZSO AGNES
Format: Patent
Sprache:eng ; slv
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Beschreibung
Zusammenfassung:The invention relates to pellets containing venlafaxine hydrochloride and a process for the preparation thereof. The pellets according to the invention are nearly spherical in shape and comprise pharmaceutically active venlafaxine hydro­chloride in an amount of at most 80 % by weight, furthermore 10 to 60 % by weight of sodium chloride and/or potassium chloride, 10 to 60 % by weight of microcrystalline cellulose and optionally other pharmaceutically acceptable excipients and/or pelletization promoting additives. Said pellets are particularly suitable to be coated with a layer ensuring a controlled release of the active ingredient.