CONTROLLED SYNTHESIS OF ZIPRASIDONE

CONTROLLED SYNTHESIS OF ZIPRASIDONE

The subject invention provides a ziprasidone composition that comprises not greater than 1000 ppm des-chloro ziprasidone, preferably not greater than about 500 ppm des-chloro ziprasidone, and more preferably not greater than about 100 ppm des-chloro ziprasidone. Methods for synthesizing and using su...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BUSCH FRANK ROBERT, LEEMAN KYLE ROBERT, HOWARD HARRY RALPH JR, GROBIN ADAM WORTH
Format: Patent
Sprache:eng ; slv
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The subject invention provides a ziprasidone composition that comprises not greater than 1000 ppm des-chloro ziprasidone, preferably not greater than about 500 ppm des-chloro ziprasidone, and more preferably not greater than about 100 ppm des-chloro ziprasidone. Methods for synthesizing and using such ziprasidone compositions are also provided.