3-amino-3-arylpropan-1-ol-derivates, their preparation and use

3-Amino-3-(hetero)aryl-propan-1-ol benzyl ethers and benzoate esters (I) are new. The 3-amino-3-(hetero)aryl-propan-1-ol benzyl ether and benzyl esters are compounds of formula (I), including their enantio and diastereoisomers, and their addition salts. A = aryl optionally containing hetero atoms; R...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	HENNIES HAGEN-HEINRICH DR, BUSCHMANN HELMUT DR, KOEGEL BABETTE-YVONNE DR, SUNDERMANN BERND DR
Format:	Patent
Sprache:	eng ; slv
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	3-Amino-3-(hetero)aryl-propan-1-ol benzyl ethers and benzoate esters (I) are new. The 3-amino-3-(hetero)aryl-propan-1-ol benzyl ether and benzyl esters are compounds of formula (I), including their enantio and diastereoisomers, and their addition salts. A = aryl optionally containing hetero atoms; R , R = 1-6C alkyl; or R + R = form 2-6C alkylidene optionally benzo-fused or substituted with phenyl; R = H or CH3; R , R = 1-6C alkyl, 3-6C cycloalkyl, phenyl, benzyl or phenethyl; or R + R = form 3-6C alkylidene or -CH2CH2OCH2CH2- ; X = group of formula (i) or (ii); R -R = H, F, Cl, Br, CHF2, CF3, OR , SR , OCF3, SO2CH3, SO2CF3, 1-6C alkyl, phenyl, CN, COOR or NO2; and R = H, 1-6C alkyl, phenyl, benzyl or phenethyl. An Independent claim is also included for the preparation of compounds (I).