Arylalkyl-pyridazinones

Aryl alkyl pyridazinone derivs. of formula (I) are new: R , R = H or A; R , R = OH, OR , SR , SO-R , SO2-R , halo, methylenedioxy, NO2, NH2, NHR or NR R ; R = phenyl opt. mono- or di-substd. by R and/or R ; Q = absent or 1-6C alkyl; R , R = NH2 NR R , NHR , NR R , NO2, halo, CN, OA, COOH or COOA; R...

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Bibliographische Detailangaben
Hauptverfasser:	JONAS ROCHUS DR, WOLF MICHAEL DR, BEIER NORBERT DR
Format:	Patent
Sprache:	eng ; slv
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Aryl alkyl pyridazinone derivs. of formula (I) are new: R , R = H or A; R , R = OH, OR , SR , SO-R , SO2-R , halo, methylenedioxy, NO2, NH2, NHR or NR R ; R = phenyl opt. mono- or di-substd. by R and/or R ; Q = absent or 1-6C alkyl; R , R = NH2 NR R , NHR , NR R , NO2, halo, CN, OA, COOH or COOA; R , R = H, 1-8C acyl (opt. substd. by 1-5F and/or Cl), COOA, SO-A, SO2A, CONH2, CONHA, CONA2, CO, COOH, CO-COOA, CO-CONH2, CO-CONHA or CO-CONA2; A = 1-6C alkyl (opt. substd. by 1-5 F and/or Cl); R , R = A, 3-7C cycloalkyl, 4-8C methylenecycloalkyl or 2-8C alkenyl; halo = F, Cl, Br or I.