PINACOL ESTER INTERMEDIATES USEFUL FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES

Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates thereof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the present methods are endothelin antagonists useful, inter alia, for th...

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Bibliographische Detailangaben
Hauptverfasser: CHENNAGIRI R. PANDIT, YADAGIRI PENDRI, XUEBAO WANG, EDUARDO J. MARTINEZ, JEFFREY S. DEPUE, KUMAR G. GADAMASETTI, RICHARD P. POLNIASZEK
Format: Patent
Sprache:eng
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Zusammenfassung:Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates thereof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the present methods are endothelin antagonists useful, inter alia, for the treatment of hypertension.