PROCESS FOR THE PREPARATION OF RETIGABINE

PROCESS FOR THE PREPARATION OF RETIGABINE

This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MILLAR, ALAN, TOCZKO, JENNIFER, FELL, FITZGERALD, RUSS, N
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator MILLAR, ALAN
TOCZKO, JENNIFER, FELL
FITZGERALD, RUSS, N
description This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_SG191309A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>SG191309A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_SG191309A13</originalsourceid><addsrcrecordid>eNrjZNAMCPJ3dg0OVnDzD1II8XBVCAhyDXAMcgzx9PdT8HdTCHIN8XR3dPL0c-VhYE1LzClO5YXS3Azybq4hzh66qQX58anFBYnJqXmpJfHB7oaWhsYGlo6GxoRVAACeaCOJ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS FOR THE PREPARATION OF RETIGABINE</title><source>esp@cenet</source><creator>MILLAR, ALAN ; TOCZKO, JENNIFER, FELL ; FITZGERALD, RUSS, N</creator><creatorcontrib>MILLAR, ALAN ; TOCZKO, JENNIFER, FELL ; FITZGERALD, RUSS, N</creatorcontrib><description>This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.</description><language>eng</language><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130731&amp;DB=EPODOC&amp;CC=SG&amp;NR=191309A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130731&amp;DB=EPODOC&amp;CC=SG&amp;NR=191309A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MILLAR, ALAN</creatorcontrib><creatorcontrib>TOCZKO, JENNIFER, FELL</creatorcontrib><creatorcontrib>FITZGERALD, RUSS, N</creatorcontrib><title>PROCESS FOR THE PREPARATION OF RETIGABINE</title><description>This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAMCPJ3dg0OVnDzD1II8XBVCAhyDXAMcgzx9PdT8HdTCHIN8XR3dPL0c-VhYE1LzClO5YXS3Azybq4hzh66qQX58anFBYnJqXmpJfHB7oaWhsYGlo6GxoRVAACeaCOJ</recordid><startdate>20130731</startdate><enddate>20130731</enddate><creator>MILLAR, ALAN</creator><creator>TOCZKO, JENNIFER, FELL</creator><creator>FITZGERALD, RUSS, N</creator><scope>EVB</scope></search><sort><creationdate>20130731</creationdate><title>PROCESS FOR THE PREPARATION OF RETIGABINE</title><author>MILLAR, ALAN ; TOCZKO, JENNIFER, FELL ; FITZGERALD, RUSS, N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SG191309A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2013</creationdate><toplevel>online_resources</toplevel><creatorcontrib>MILLAR, ALAN</creatorcontrib><creatorcontrib>TOCZKO, JENNIFER, FELL</creatorcontrib><creatorcontrib>FITZGERALD, RUSS, N</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MILLAR, ALAN</au><au>TOCZKO, JENNIFER, FELL</au><au>FITZGERALD, RUSS, N</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR THE PREPARATION OF RETIGABINE</title><date>2013-07-31</date><risdate>2013</risdate><abstract>This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_SG191309A1
source esp@cenet
title PROCESS FOR THE PREPARATION OF RETIGABINE
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T04%3A32%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=MILLAR,%20ALAN&rft.date=2013-07-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ESG191309A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true