ANTI-DIABETIC COMPOUNDS

The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	VIOLAND, BERNARD NORMAN, PALANKI, MOORTHY SITHARAMAIAH SURIYANARAYANA, PARSONS, ERIN, KRISTEN, ISHINO, TETSUYA, DAS, TAPAN, KANTI, HODGE, TAMARA, SHAFER, LEVIN, NANCY, JANE
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.