NOVEL CRYSTALS AND PROCESS OF MAKING 5-({[2-AMINO-3-(4-CARBAMOYL-2,6-DIMETHYL-PHENYL)-PROPIONYL]-[1-(4-PHENYL-1H-IMIDAZOL-2-YL)-ETHYL]-AMINO}-METHYL)-2-METHOXY- BENZOIC ACID

NOVEL CRYSTALS AND PROCESS OF MAKING 5-({[2-AMINO-3-(4-CARBAMOYL-2,6-DIMETHYL-PHENYL)-PROPIONYL]-[1-(4-PHENYL-1H-IMIDAZOL-2-YL)-ETHYL]-AMINO}-METHYL)-2-METHOXY- BENZOIC ACID

NOVEL CRYSTALS AND PROCESS OF MAKING 5-(([2-AMINO-3-(4-CARBAMOYL 2,6-DIMETHYL-PH ENYL)-PROPIO NYLM1-(4-PHENYL-1H-IMIDAZOL-2-YL)-ETHYLF AMIN 0}-METHYL)-2-METH OXY-BENZOIC ACIDAbstractThe present invention relates to a novel crystal of 5-({[2-amino-3-(4-carbamoy1-2, 6-dimethyl-pheny1)-propiony1]-11-(4...

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Bibliographische Detailangaben
Hauptverfasser: ANZALONE, LUIGI, VILLANI, FRANK J, FEIBUSH, PENINA, FEGELY, BARRY, TELEHA, CHRISTOPHER ALLAN
Format: Patent
Sprache:eng
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Zusammenfassung:NOVEL CRYSTALS AND PROCESS OF MAKING 5-(([2-AMINO-3-(4-CARBAMOYL 2,6-DIMETHYL-PH ENYL)-PROPIO NYLM1-(4-PHENYL-1H-IMIDAZOL-2-YL)-ETHYLF AMIN 0}-METHYL)-2-METH OXY-BENZOIC ACIDAbstractThe present invention relates to a novel crystal of 5-({[2-amino-3-(4-carbamoy1-2, 6-dimethyl-pheny1)-propiony1]-11-(4-pheny1-1 H-imidazol-2-y1)-ethyl]amino} -methy1)2- methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4- carbamoy1-2,6-dimethyl-phenyo-propiony1]-0-(4-phenyl-1 H-imid azol-2-y1)-ethyl}amino} - methyl)-2-methoxy-benzoic acid. Figure 1.