5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory,...

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Hauptverfasser: PRASIT, PETPIBOON, PEPPI, HUTCHINSON, JOHN, HOWARD, STOCK, NICHOLAS, SIMON, SEIDERS, THOMAS, JON, TRUONG, YEN, PHAM, ARRUDA, JEANNIE, M, LI, YIWEI, HADDACH, MUSTAPHA, MORAN, MARK, ZUNIC, JASMINE, ELEANOR, STEARNS, BRIAN, ANDREW, ROPPE, JEFFREY, ROGER, EVANS, JILLIAN, F, WANG, BOWEI, SCOTT, JILL, MELISSA
Format: Patent
Sprache:eng
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Zusammenfassung:Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.Fig. 15