INHIBITORS OF THE HEDGEHOG PATHWAY

INHIBITORS OF THE HEDGEHOG PATHWAYAbstractThe present invention is directed to a compound of Formula (I) or a single isomer thereof; where the compound is optionally as a phamaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formu...

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Hauptverfasser: RIDGWAY, BRIAN HUGH, BAJJALIEH, WILLIAM, WANG, YONG, TESFAI, ZEROM, HUYNH, TAI PHAT, FORSYTH, TIMOTHY PATRICK, CHEN, JEFF, MANN, GRACE, SHI, XIAN, MAC, MORRISON B, TAKEUCHI, CRAIG STACY, SANGALANG, JOAN C, MARLOWE, CHARLES K, EPSHTEYN, SERGEY, KIM, BYUNG GYU, BAHCECI, SULEYMAN, LEAHY, JAMES W, LEE, MATTHEW SANGYUP, LEWIS, GARY L
Format: Patent
Sprache:eng
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Zusammenfassung:INHIBITORS OF THE HEDGEHOG PATHWAYAbstractThe present invention is directed to a compound of Formula (I) or a single isomer thereof; where the compound is optionally as a phamaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula 1, and methods of using a Compound of Formula (I) to treat cancer.