PREPARATION OF POLYMER CONJUGATES OF THERAPEUTIC, AGRICULTURAL, AND FOOD ADDITIVE COMPOUNDS

PREPARATION OF POLYMER CONJUGATES OF THERAPEUTIC, AGRICULTURAL, AND FOOD ADDITIVE COMPOUNDS

PREPARATION OF POLYMER CONJUGATES OF THERAPEUTIC, AGRICULTURAL AND FOOD ADDITIVE COMPOUNDSAbstractThis invention provides an improved synthesis of polymer conjugates of formula (I), of agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation o...

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Hauptverfasser: KONRADI, ANDREI W, SMITH, JENIFER L
Format: Patent
Sprache:eng
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Zusammenfassung:PREPARATION OF POLYMER CONJUGATES OF THERAPEUTIC, AGRICULTURAL AND FOOD ADDITIVE COMPOUNDSAbstractThis invention provides an improved synthesis of polymer conjugates of formula (I), of agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using "Mitsunobu" or related reaction conditions.Formula (I) CB C_A-) (I)