Methods

We disclose a method of diagnosis of a cancer in an individual, the method comprising detecting modulation of expression of a Sprouty1 sequence. A method of treatment or prophylaxis of a cancer in an individual is also disclosed, the method comprising modulating the amount of a Sprouty1 polypeptide...

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Hauptverfasser: TING LING LO, YUSOFF PERMEEN, CHEE WAI FONG
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:We disclose a method of diagnosis of a cancer in an individual, the method comprising detecting modulation of expression of a Sprouty1 sequence. A method of treatment or prophylaxis of a cancer in an individual is also disclosed, the method comprising modulating the amount of a Sprouty1 polypeptide or nucleic acid in a cell of an individual. The methods are suitable for detection and treatment of breast cancer, based on our demonstration that Sprouty1 expression is down-regulated in this disease.