MASP INHIBITORY COMPOUNDS AND USES THEREOF

MASP INHIBITORY COMPOUNDS AND USES THEREOF

The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases...

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Hauptverfasser: TERSTEEGEN, Adrian, NEUBAUER, Thomas, ZUBOV, Dmitry, GLATZ, Marie, DREHER, Jan, BAUMANN, Lars, POETHKO, Thorsten, BIERER, Donald, TERJUNG, Carsten, FLAMME, Ingo, HOLTON, Simon, QIU, Yibo, XIONG, Jiancheng, JUHL, Cathleen
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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creator TERSTEEGEN, Adrian
NEUBAUER, Thomas
ZUBOV, Dmitry
GLATZ, Marie
DREHER, Jan
BAUMANN, Lars
POETHKO, Thorsten
BIERER, Donald
TERJUNG, Carsten
FLAMME, Ingo
HOLTON, Simon
QIU, Yibo
XIONG, Jiancheng
JUHL, Cathleen
description The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of renal and cardiovascular disorders and of ischemia reperfusion injuries.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title MASP INHIBITORY COMPOUNDS AND USES THEREOF
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